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Immunology

Life is a health journey and we, at Sanofi, hope to make a difference in the lives of people affected by immune disorders by developing innovative therapies. Immune disorders are diseases or conditions caused by a dysfunction of the immune system and include allergy, asthma and autoimmune diseases.

As a health journey partner, we are dedicated to bringing new options to patients with an unmet need. In collaboration with Regeneron Pharmaceuticals, our current therapies for atopic dermatitis and rheumatoid arthritis are approved in the United States, Canada and Europe and we are seeking approvals in a number of other countries globally.

Current research conducted by Sanofi Genzyme, our global specialty care business unit, includes investigational treatments for asthma, nasal polyps, and eosinophilic esophagitis, each of which represent an area of significant need including those in emerging markets (1).

Moderate-to-Severe Atopic Dermatitis

1.6 million patients is, approximately in the US, the figure of prevalence of adults with moderate-to-severe AD whose disease is not adequately controlled with topical prescription therapies. 10% of people with AD say their work performance is affected.

Atopic dermatitis (AD), a form of eczema, is a chronic inflammatory disease with symptoms often appearing as a rash on the skin. Moderate-to-severe atopic dermatitis is characterized by rashes often covering much of the body, and can include intense, persistent itching and skin dryness, cracking, redness, crusting, and oozing. Itch is one of the most burdensome symptoms for patients and can be debilitating. In addition, patients with moderate-to-severe atopic dermatitis experience a substantial burden of disease, including skin lesions, intense pruritus, and an impact on quality of life, such as sleep and symptoms of anxiety and depression.

Rheumatoid arthritis

About 1.3 million people suffer from rheumatoid arthritis in the United States - 2.9 million in the European Union - 1.4 million in Japan - The majority of whom are women

Rheumatoid arthritis – commonly known as RA – is a chronic and debilitating autoimmune disease that primarily affects the joints, connective tissues, muscle, tendons, and fibrous tissue, causing pain, deformity and disability. There are more than 150 rheumatic conditions, with RA being one of the most common.

Although RA is typically thought of as a joint disease, the effects of RA can go beyond the joints. Living with RA can interfere with everyday life, and simple tasks can become difficult or take longer to complete. The symptoms of RA can also lead to stress or anxiety.

For more information about our work in Immunology, please consult the Sanofi Genzyme website.

(1) Emerging markets: world excluding U.S., Canada, Western Europe (France, Germany, UK, Italy, Spain, Greece, Cyprus, Malta, Belgium, Luxembourg, Portugal, the Netherlands, Austria, Switzerland, Sweden, Ireland, Finland, Norway, Iceland, Denmark), Japan, South Korea, Australia and New Zealand.