Amit, living with asthma in Israel
On the surface, atopic dermatitis (AD), a chronic skin condition, and asthma, a respiratory disease, may not appear to have much in common, but beneath the surface, both are driven by an immune response called type 2 inflammation.
Recent scientific developments have shown that excessive type 2 inflammation underlies different inflammatory diseases (atopic dermatitis, asthma, etc).1,2,3 People living with type 2 inflammatory diseases, like Tzippy from Israel, who has AD, and Amit, who has asthma and is also from Israel, often face substantial difficulties and limitations as a result of often unpredictable symptoms.
Here are their stories.
Growing up with AD: Tzippy
Tzippy has lived with AD since she was a baby. After three hospitalizations while she was a young child, Tzippy’s family traveled all over Europe to try and find relief for her symptoms. As an adolescent, she was shy and her disease caused her to feel isolated from her peers, who didn’t understand what she was going through.
Now a mother herself to a child with AD, Tzippy hopes to teach her daughter that she will be able to do whatever she wants in her life.
Taking Control of Asthma: Amit
Amit had always been active. She did gymnastics when she was young and then as a teenager became an avid runner. When she was 18, Amit began coughing badly after runs and couldn’t catch her breath. She was diagnosed with mild asthma.
Shortly after, Amit joined the army, but her asthma symptoms quickly worsened, and she found herself hospitalized frequently with severe asthma attacks. She was released from the army and had to miss out on the things she enjoyed doing most like running and socializing with friends.
Since her diagnosis of severe asthma, Amit has learned how to better manage her symptoms. She is studying to become a nurse and says her experience will help her to speak to patients with true empathy and understanding.
1 N. A. Gandhi, B. L. Bennett and N. M. Graham. Targeting key proximal drivers of type 2 inflammation in disease. Nature Reviews Drug Discovery. 2016; 15(1):35-50.
2 S. Carr, E. Chan, and W. Watson. Eosinophilic esophagitis. Allergy, Asthma & Clinical Immunology. 2018; 14(1):58.
3 J. W. Steinke and J. M. Wilson. Aspirin-exacerbated respiratory disease: pathophysiological insights and clinical advances. Journal of Asthma and Allergy. 2016; 9:37-43.