Fighting against some infectious diseases



Contributing to the eradication, elimination and control of some infectious diseases

Tuberculosis & latent tuberculosis infection

Tuberculosis has become the world’s deadliest infectious disease, killing more than HIV and Malaria. This contagious disease, caused by the bacteria Mycobacterium tuberculosis, is spread through respiratory droplets.

In 2017, there were:

10 million
new cases, eight countries gathering 2/3 of TB cases
1.6 million
deaths, the vast majority of them in low- and middle-income countries1
About 23%
of the world population has latent tuberculosis

Today, about 1.7 million of the world’s population has latent tuberculosis infection (LTBI), the stage when TB lies a dormant killer in the rel="noopener noreferrer" body without symptoms. Some persons are at greater risk of developing the disease : treating them successfully is key to changing the course of this epidemic.

As a health journey partner, Sanofi is strongly committed to stepping up the fight to eliminate tuberculosis.

We are developing a new global approach to contribute to eliminating tuberculosis:

  • Global awareness campaign to expand the treatment coverage of latent tuberculosis infection
  • New tools to improve educational efforts for healthcare professionals and general public
  • Bolder partnerships and support to TB prevention and care to countries most in need
  • Development of innovative and cost-effective therapeutic solutions, to answer unmet needs

 

  1. Global tuberculosis report 2018, accessed on Sept. 19th 2018:
    http://www.who.int/tb/publications/global_report/en/

LEARN MORE ON TUBERCULOSIS & LATENT TUBERCULOSIS INFECTION

Young woman suffering of tuberculosis
World TB Day 2018
Factsheet about tuberculosis
Sanofi Fighting tuberculosis factsheet
Awareness campaign
Discover our awareness campaign
Latent Tuberculosis Infection guidelines
Latent Tuberculosis Infection – Updated and consolidated guidelines for programmatic management, WHO

Polio

 Polio


We have developed substantial expertise in the field of infectious diseases and are committed to contributing to the eradication, elimination and control of certain infectious diseases.

Because life is a health journey, we work with international organizations (Gavi, the Vaccine Alliance, WHO and UNICEF) towards a world where vaccination could ensure that people no longer suffer from a preventable disease. We are committed to providing quality vaccines at affordable prices.

We are a longstanding partner of the Global Polio Eradication Initiative (GPEI) providing oral polio vaccines since 1999 and injectable polio vaccines since 2014 with the aim of eradicating the disease.

In 2016, we delivered 42 million doses of IPV standalone to UNICEF for GAVI countries.

Watch the video

 

Malaria

Malaria is one of the most deadly infectious diseases in the world. According to the World Health Organization, there were approximately 214 million cases and 438,000 deaths due to malaria in 2015, mostly among African children. In Africa, one child dies of malaria every two minutes.

As a health journey partner, we supply our ASAQ Winthrop® drug, a fixed dose combination of artesunate-amodiaquine developed in partnership with the Drugs for Neglected Diseases Initiative (DNDi), and for which we did not seek patent protection, at preferential prices. Since its launch in 2007, ASAQ Winthrop® has enabled the treatment of over 400 million malaria attacks, including more than 43 million in 2016.

We also collaborate with national malaria control programs, ministries of Education and NGOs, and developed the Schoolchildren Against Malaria program, in order to promote prevention in schools in sub-Saharan Africa. In 2016, the program was still active in Gabon and Mozambique and close to 10,000 children and school staff benefited from awareness programs. In 2017, additional awareness initiatives took place in Cameroon, Guinea and Togo.

Malaria

Learn more on malaria 

Sleeping sickness

Sleeping sickness threatens millions of people in sub-Saharan Africa. This disease is fatal if not treated.

Because we are a health journey partner, thanks to our partnership with the WHO which started in 2001, 34 million people have been screened for sleeping sickness and close to 200 000 patients have been treated. Moreover, since 2009, we entered into an innovative partnership with the Drugs for Neglected Diseases Initiative (DNDi) for the development of fexinidazole, oral monotherapy for all stages of the disease. DNDi has carried out clinical testing and we are responsible for industrial development, production and regulatory submission. An oral monotherapy for sleeping sickness can contribute to simplifying treatment by avoiding systematic hospitalization and removing the need of lumbar punctures for patients.

The Phase II/III clinical trials completed in the Democratic Republic of Congo and Central African Republic achieved the primary endpoints, enabling us to pursue submission for approval by health authorities. Fexinidazole could represent a therapeutic breakthrough which will support sustainable elimination efforts as set out by the World Health Organization’s roadmap for 2020.

Sleeping sickness

Learn more on sleeping sickness